A seroma is a collection of fluid composed of fat, serum, and lymph. Seromas commonly develop following surgery as the body tries to fill in the dead space created during surgery. 

Etiology & Pathophysiology

  • Accumulation of serous fluid in dead space → often occurs after hernia and breast surgery, but can occur after any surgery
  • Thought to arise due to lymphatic and vascular drainage disruption through soft tissue dissection that occurs during surgery

Prevention

  • Proposed techniques to reduce seroma formation (results are INCONSISTENT)
  • Minimize dead space
    • Excise excess skin
    • Use fibrin sealant
    • Quilting sutures
    • Medical talc
  • Drain dead space

Presentation

  • Pressure-like sensation at seroma
  • Palpable subcutaneous fluid collection
  • Swelling, pain, and erythema may be present if the seroma is infected

Imaging

  • Ultrasound: anechoic fluid collection
  • CT

Treatment

  • Asymptomatic seroma → often resolve spontaneously
  • Symptomatic seroma (often when seroma is >100 cc) → sterile aspiration, pressure dressing
  • Refractory seroma → drain placement, heal by secondary intention
  • Infected seroma
    • Surgical drainage and antibiotics
    • Explant exposed prosthetic implants when infection is severe